Key Concept

Key Evidence: In a study of a 2003 outbreak of pertussis in the U.S., including 17 cases among healthcare workers, researchers estimated that vaccinating healthcare workers would prevent nearly 50% of disease exposures by healthcare workers per year.

Calugar A, Ortega-Sanchez I, Tiwari T et al. 2006. Nosocomial pertussis: Costs of an outbreak and benefits of vaccinating health care workers. CID. 42.
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Key Evidence: Using data on the spread of Ebola from person to person during historical Ebola outbreaks to compare vaccination strategies, researchers found that prophylatically vaccinating all healthcare workers would have decreased the number of disease cases in the 2014 epidemics in Guinea and Nigeria by 60-80%.

Coltart CE, Johnson AM, Whitty CJ 2015. Role of healthcare workers in early epidemic spread of Ebola: policy implications of prophylactic compared to reactive vaccination policy in outbreak prevention and control. BMC Medicine. 13(271).
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