VoICE Immunization Evidence: Maternal Health

Key Concept

Key Evidence: Mothers infected with rubella virus during the first trimester of pregnancy can give birth to children with permanent disabilities such as intellectual impairment, autism, blindness, deafness, and cardiac defects. The infection is completely preventable if mothers are vaccinated before pregnancy.

Andrus, J.K., Cochi, S.L., Cooper, L.Z., et al 2016. Combining global elimination of measles and rubella with strengthening of health systems in developing countries. Health Affairs. 35(2):327-33.

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Key Evidence: Pregnant women are at particularly high risk of serious illness and death from a variety of bacterial and viral diseases, such as influenza, pneumococcal pneumonia, and Group B strep, for which vaccines exist or are in development. Vaccine-preventable diseases in pregnancy are associated with adverse pregnancy outcomes such as spontaneous abortion, congenital anomalies, preterm birth, and low birth weight.

Swamy GK, Beigi RH 2015. Maternal benefits of immunization during pregnancy. Vaccine. 33.

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