VoICE Immunization Evidence: Growth, Development, and Nutrition
Malnourished children are at greater risk of death from potentially vaccine-preventable diseases than children with no significant signs of malnourishment.
Findings of a systematic review evaluating the relationship between pneumonia and malnourishment found that severely malnourished children in developing countries had 2.5 to 15 times the risk of death. For children with moderate malnutrition, the risk of death ranged from 1.2 to 36.
Chisti, M.J., Tebruegge, M., La Vincente, S., et al. 2009. Pneumonia in severely malnourished children in developing countries – mortality risk, aetiology and validity of WHO clinical signs: a systematic review. Tropical Medicine and International Health. 14(10).
A study of children under 5 years of age in Dhaka Bangladesh found that severely malnourished children were at a significantly increased risk (nearly 8x) of death from diarrhea than those who were not severely malnourished.
Chisti, M.J., Pietroni, M.A., Smith, J.H., et al 2011. Predictors of death in under-five children with diarrhoea admitted to a critical care ward in an urban hospital in Bangladesh. Acta Paediatrica. 100:e275-9.