VoICE Immunization Evidence: Antimicrobial Resistance
The pneumococcal conjugate vaccine has been shown to significantly reduce the rate of antibiotic and multi-drug resistant strains of pneumococcal disease affecting children.
This study from South Africa demonstrates significant declines in invasive pneumococcal disease cases caused by bacteria that are resistant to one or more antibiotics. In fact, the rate of infections resistant to two different antibiotics declined nearly twice as much as infections that could be treated with antibiotics.
Von Gottberg, A., de Gouveia, L., Tempia, S., et al 2014. Effects of pneumococcal vaccine in invasive pneumococcal disease in South Africa. New England Journal of Medicine. 371:1889-99.