VoICE Immunization Evidence: Antimicrobial Resistance

Key Idea

The US CDC identifies the use of vaccines as one of the 4 critical steps for controlling the spread of antibiotic resistance.

Centers for Disease Control and Prevention 2013. Antibiotic resistance threats in the United States, 2013 (Report).

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A systematic review of studies from India found that prior to widespread use of the pneumococcal conjugate vaccine, antibiotic resistance in serious pneumoccocal infections among Indian children has been common. Penicillin resistance was found in 10% of invasive pneumococcal disease (IPD) cases, while trimethoprim/sulfamethoxazole resistance was found in more than 80% of these cases.

Singh, J., Sundaresan, S., Manoharan, A. and Shet, A. 2017. Serotype distribution and antimicrobial susceptibility pattern in children≤ 5 years with invasive pneumococcal disease in India–A systematic review. Vaccine. 35(35), pp.4501-4509.

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