VoICE : Search Immunization Evidence

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The VoICE tool is a compendium of the many direct and downstream impacts of vaccine-preventable disease and immunization. The database contains summary explanations of the link between immunization and each impact, as well as sources of evidence for each link. You can browse the VoICE tool by topic, or use the filters to find results based on topic, disease or vaccine, location and published year.

15 Key Ideas, 8 Sources
Key Idea

A study of over 80,000 children in Kenya designed to understand the role of inadequate health systems on childhood survival beyond 59 months of age showed that a higher per capita density of heath faciities resulted in a 25% reduction in the risk of death. However, user fees for sick-child visits increased the risk of death by 30%.

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Key Idea

The detection of H1N1 influenza virus in Mexico in 2009, and subsequently throughout other countries in the Americas, benefited from the laboratory experience with measles and rubella in the region…. [leading to] the rapid detection of and response to what eventually became a novel pandemic virus.

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Key Idea

Tens of millions of volunteers, social mobilizers, and health workers have participated in the Global Polio Eradication Initiative. The program contributes to efforts to deliver other health benefits, including health systems strengthening. Polio eradication legacy efforts include documenting and applying the lessons learned from polio eradication, and transitioning the capacities, assets and processes of polio to other key health priorities.

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Key Idea

Introduction of HPV vaccine in Rwanda occurred through a new school-based delivery program which provided the opportunity to offer additional health services to all school-children (girls and boys) including health promotion sessions, de-worming and opportunities for voluntary, free circumcision.

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Key Idea

Polio eradication investments in health infrastructure have been concentrated in some of the lowest performing health systems in the world, challenged internally by geography, poverty, armed conflict, etc. These assets can be leveraged to improve the health system and immunization overall nationally.

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Key Idea

Mothers infected with rubella virus during the first trimester of pregnancy can give birth to children with permanent disabilities such as intellectual impairment, autism, blindness, deafness and cardiac defects. The infection is completely preventable if mothers are vaccinated before pregnancy.

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Key Idea

Tens of millions of volunteers, social mobilizers, and health workers have participated in the Global Polio Eradication Initiative. The program contributes to efforts to deliver other health benefits, including health systems strengthening. Polio eradication legacy efforts include documenting and applying the lessons learned from polio eradication, and transitioning the capacities, assets and processes of polio to other key health priorities.

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Key Idea

In October 2012, responding to the declaration by the World Health Organization of polio eradication as a global public health emergency, and to improve its national response, the Government of Nigeria used the Incident Management System (IMS) to establish a national Emergency Operations Center (EOC) as part of a new national emergency plan for the global polio eradication initiative. The use of IMS through the EOC changed the operational tempo, accountability measures, and programmatic success of the polio program. This existing infrastructure was leveraged to contain the outbreak of Ebola.

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Key Idea

In the Americas, a platform built to secure polio eradication has been expanded to help track, control, prevent and monitor immunization impact for measles and rubella. In India, highly trained polio health workers have become the basis for a trained workforce working towards the elimination of measles and rubella and helping ensure India’s certification by WHO for having eliminated maternal and neonatal tetanus.

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Key Idea

A systematic review of studies examining the broader economic impact of vaccination in low-middle income countries (LMICs) found that vaccination programs may improve the financial sustainability and affordability of healthcare programs in LMICs. The use of vaccines as part of a treatment cluster, or in combination with other infrastructure projects (such as water management systems) to maximize community health outcomes, offers opportunities for cost sharing between programs.

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Key Idea

The American Academy of Pediatrics and the International Pediatric Association were included as partners in the measles and rubella elimination initiative, allowing for more direct collaboration around the interactions of primary health and immunization services and concerns.

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Despite delivery of HPV vaccine through a mechanism new to the country (school-based campaigns), the HPV vaccine integrated well into the Rwandan health system and caused no major disruptions. In fact, its introduction resulted in strengthened collaboration between the Ministries of Health and Education and provision of additional health services to school-children including health promotion sessions and de-worming.

View Source >

Key Idea

The detection of H1N1 influenza virus in Mexico in 2009, and subsequently throughout other countries in the Americas, benefited from the laboratory experience with measles and rubella in the region…. [leading to] the rapid detection of and response to what eventually became a novel pandemic virus.

View Source >

In October 2012, responding to the declaration by the World Health Organization of polio eradication as a global public health emergency, and to improve its national response, the Government of Nigeria used the Incident Management System (IMS) to establish a national Emergency Operations Center (EOC) as part of a new national emergency plan for the global polio eradication initiative. The use of IMS through the EOC changed the operational tempo, accountability measures, and programmatic success of the polio program. This existing infrastructure was leveraged to contain the outbreak of Ebola.

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Key Idea

This paper presents the first cost-benefit comparison of improved water supply investments and cholera vaccination programs. The study results showed that improved water supply interventions combined with targeted cholera vaccination programs are much more likely to yield attractive cost-benefit ratio outcomes than a community-based vaccination program alone.

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A systematic review of studies examining the broader economic impact of vaccination in low-middle income countries (LMICs) found that vaccination programs may improve the financial sustainability and affordability of healthcare programs in LMICs. The use of vaccines as part of a treatment cluster, or in combination with other infrastructure projects (such as water management systems) to maximize community health outcomes, offers opportunities for cost sharing between programs.

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Key Idea

A recent review looks at evidence linking vaccinations in early infancy to childhood development services. BCG and DPT have the highest coverage of any vaccines worldwide and are typically administered within 6 weeks of birth. This timing offers the opportunity to deliver a range of early childhood development interventions such as newborn hearing screening, sickle cell screening, treatment and surveillance, maternal education around key newborn care issues such as jaundice, and tracking early signs of poor growth and nutrition.

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Key Idea

Despite delivery of HPV vaccine through a mechanism new to the country (school-based campaigns), the HPV vaccine integrated well into the Rwandan health system and caused no major disruptions. In fact, its introduction resulted in strengthened collaboration between the Ministries of Health and Education and provision of additional health services to school-children including health promotion sessions and de-worming.

View Source >