Publication

Cost-effectiveness of analysis of pertussis vaccination during pregnancy in Japan

Authored by:

Hoshi S-L, Seposo X, Okubo K, et al.

Full Citation:

Hoshi S-L, Seposo X, Okubo K, et al. 2018. Cost-effectiveness of analysis of pertussis vaccination during pregnancy in Japan. Vaccine. 36.

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Additional key concepts from this publication:

Maternal immunization offers an opportunity to protect the mother and fetus, but also passes this protection on to the infant after birth.

Key Evidence: In Japan, which has experienced a re-emergence of pertussis among adolescents and adults, vaccinating pregnant women with the Tdap vaccine would be cost effective in preventing the illness in young infants (<3 months of age) and in mothers, according to the WHO definition of cost effectiveness. This is true even if only 50% of pregnant women receive the vaccine.

The indirect benefit of immunization to unvaccinated individuals (herd immunity) increases the cost-effectiveness of vaccines.