VoICE Immunization Evidence

Cost-effectiveness of pertussis vaccination during pregnancy in the US

Authored by: Atkins KE, Fitzpatrick MC, Galvani AP, Townsend JP

Appears in:

Key Concept

Key Evidence: Pertussis causes nearly 200,000 deaths in children worldwide, nearly all in infants too young to be vaccinated. Vaccinating pregnant women against pertussis with a single dose of Tdap vaccine would be 89% effective in protecting infants against the disease over their first 2 months of life and would reduce pertussis incidence in newborns in the U.S. by 68% (assuming 75% of mothers are vaccinated).

Key Concept

Key Evidence: Pertussis causes nearly 200,000 deaths in children worldwide, nearly all in infants too young to be vaccinated. Vaccinating pregnant women against pertussis with a single dose of Tdap vaccine would be 89% effective in protecting infants against the disease over their first 2 months of life and would reduce pertussis incidence in newborns in the U.S. by 68% (assuming 75% of mothers are vaccinated). This strategy is cost-effective, whereas vaccinating the father before the birth or vaccinating parents and/or other family members after the child is born would not be.

From the VoICE Editors: The analysis assumes a vaccination cost of ≈$44 per dose.

Published In

Atkins KE, Fitzpatrick MC, Galvani AP, Townsend JP 2016. Cost-effectiveness of pertussis vaccination during pregnancy in the US. American Journal of Epidemiology. 183(12).

Disease or Vaccine