Publication

Effect of a conjugate pneumococcal vaccine on the occurrence of respiratory infections and antibiotic use in day-care center attendees

Authored by:

Dagan, R., Sikuler-Cohen, M., Zamir, O., et al

Full Citation:

Dagan, R., Sikuler-Cohen, M., Zamir, O., et al 2001. Effect of a conjugate pneumococcal vaccine on the occurrence of respiratory infections and antibiotic use in day-care center attendees. Pediatric Infectious Disease Journal. 20(10).

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Additional key concepts from this publication:

Use of vaccines decreases the need to use antibiotics to treat disease, thus reducing the opportunity for the development of antimicrobial resistance.

Key Evidence: Evaluation of the ability of pneumococcal conjugate vaccine to reduce the occurrence of respiratory infections and the resultant antibiotic drug use was conducted among day care attendees in Israel. It was observed that children who had received the 9-valent conjugate vaccine showed a 17% overall reduction in antibiotic usage. In particular, a 10% reduction in days of antibiotic usage for upper respiratory tract infections, 47% fewer days of antibiotic usage for lower respiratory tract infections, and 20% fewer days of antibiotic usage for otitis media (ear infections) when compared to children who did not receive PCV.