Publication

Effectiveness of live attenuated influenza vaccine in preventing amoxicillin prescribing in preschool children: a self-controlled case series study

Authored by:

Hardelid P, Ghebremichael-Weldeselassie Y, Whitaker H et al.

Full Citation:

Hardelid P, Ghebremichael-Weldeselassie Y, Whitaker H et al. 2018. Effectiveness of live attenuated influenza vaccine in preventing amoxicillin prescribing in preschool children: a self-controlled case series study. Journal of Antimicrobial Chemotherapy. 73.

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Additional key concepts from this publication:

Use of vaccines decreases the need to use health services and treatments, like antibiotics, to treat disease.

Key Evidence: Among 33,000 preschool children in the UK (who received at least one prescription of amoxicillin) there were ~15% fewer amoxicillin prescriptions given during the influenza season to children who had received the live attenuated influenza vaccine than among children who were not vaccinated. This suggests that flu vaccination may lead to a reduction in excess, inappropriate prescribing of antibiotics for influenza in children.