Publication

Effects of pneumococcal vaccine in invasive pneumococcal disease in South Africa

Authored by:

Von Gottberg, A., de Gouveia, L., Tempia, S., et al.

Full Citation

Von Gottberg, A., de Gouveia, L., Tempia, S., et al. 2014. Effects of pneumococcal vaccine in invasive pneumococcal disease in South Africa. New England Journal of Medicine. 371(20).

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Additional key concepts from this publication:

The pneumococcal conjugate vaccine has been shown to significantly reduce the rate of antibiotic and multi-drug resistant strains of pneumococcal disease.

Key Evidence: This study from South Africa demonstrates significant declines in invasive pneumococcal disease cases caused by bacteria that are resistant to one or more antibiotics. In fact, the rate of infections resistant to two different antibiotics declined nearly twice as much as infections that could be treated with antibiotics.