VoICE Immunization Evidence

Estimating the herd immunity effect of rotavirus vaccine

Authored by: Pollard, S.L., Malpica-Llanos, T., Friberg, I.K., . . Walker, N

Appears in:

From the VoICE Editors

The herd effect represents the additional reduction in diarrhea hospitalizations observed in studies beyond the expected reduction given vaccine efficacy and reported coverage rates.

Key Idea

A meta-analysis conducted of data from studies measuring the impact of rotavirus vaccine (RVV) on severe gastroenteritis morbidity and mortality, reported a median herd immunity effect for severe rotavirus gastroenteritis in children less than one year of age of 22% (US and El Salvador).  In studies in Latin America reporting an all-cause gastroenteritis benefit the median herd effect for severe gastroenteritis was 24.9%.

Published In

Pollard, S.L., Malpica-Llanos, T., Friberg, I.K., . . Walker, N 2015. Estimating the herd immunity effect of rotavirus vaccine. Vaccine. 33(32).

Disease or Vaccine