Publication

Human papillomavirus-associated subsequent malignancies among long-term survivors of pediatric and young adult cancers

Authored by:

Ojha, R.P., Tota, J.E., Offutt-Powell, T.N., et al.

Full Citation:

Ojha, R.P., Tota, J.E., Offutt-Powell, T.N., et al. 2013. Human papillomavirus-associated subsequent malignancies among long-term survivors of pediatric and young adult cancers. PLOS ONE. 8(8).

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Additional key concepts from this publication:

Those with cancer are at greater risk of some life-threatening vaccine-preventable infections.

Key Evidence: In a US-based study of more than 65,000 longterm survivors of pediatric and young adult cancers spanning nearly three decades, researchers found an increased risk of later HPV infections and malignancies among these survivors. Female survivors of childhood and young adult cancers were found to have a 40% greater chance of developing HPV-associated malignancies compared to cancer-naïve females. This risk was even greater in male cancer survivors who had a 150% relative excess of HPV malignancies compared to cancer-naive males.