Publication

Invasive pneumococcal disease among immunocompromised persons: implications for vaccination programs

Authored by:

Shigayeva, A., Rudnick, W., Green, K., et al

Full Citation:

Shigayeva, A., Rudnick, W., Green, K., et al 2016. Invasive pneumococcal disease among immunocompromised persons: implications for vaccination programs. Clinical Infectious Disease. 62(2).

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Additional key concepts from this publication:

Vaccines are critical for malnourished and immunocompromised children.

Key Evidence: In a long-term study of Canadian surveillance data researchers found that immunocompromised people were at a 12-fold risk of invasive pneumococcal disease (IPD) compared to healthy people. In addition, the risk of death from IPD in immunocompromised people was found to be 30-80% higher than healthy individuals who had contracted IPD. 10 years after introduction of PCV7 in Canada, the incidence of IPD due to serotypes included in the vaccine had decreased by 90%.

Vaccine-preventable diseases disproportionately affect people with poorer overall health.