Publication

Serotype distribution and antimicrobial susceptibility pattern in children≤ 5 years with invasive pneumococcal disease in India–A systematic review

Authored by:

Singh, J., Sundaresan, S., Manoharan, A., et al.

Full Citation:

Singh, J., Sundaresan, S., Manoharan, A., et al. 2017. Serotype distribution and antimicrobial susceptibility pattern in children≤ 5 years with invasive pneumococcal disease in India–A systematic review. Vaccine. 35(35).

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Additional key concepts from this publication:

The use of vaccines is a critical step in controlling the occurrence of antibiotic-resistant infections.

Key Evidence: A systematic review of studies from India found that prior to widespread use of the pneumococcal conjugate vaccine, antibiotic resistance in serious pneumoccocal infections among Indian children has been common. Penicillin resistance was found in 10% of invasive pneumococcal disease (IPD) cases, while trimethoprim/sulfamethoxazole resistance was found in more than 80% of these cases.