VoICE Immunization Evidence

Serotype distribution and antimicrobial susceptibility pattern in children≤ 5 years with invasive pneumococcal disease in India–A systematic review

Authored by: Singh, J., Sundaresan, S., Manoharan, A. and Shet, A.

Appears in:

Key Idea

A systematic review of studies from India found that prior to widespread use of the pneumococcal conjugate vaccine, antibiotic resistance in serious pneumoccocal infections among Indian children has been common. Penicillin resistance was found in 10% of invasive pneumococcal disease (IPD) cases, while trimethoprim/sulfamethoxazole resistance was found in more than 80% of these cases.

Published In

Singh, J., Sundaresan, S., Manoharan, A. and Shet, A. 2017. Serotype distribution and antimicrobial susceptibility pattern in children≤ 5 years with invasive pneumococcal disease in India–A systematic review. Vaccine. 35(35), pp.4501-4509.