Infants less than 2 months old are too young to be vaccinated against pertussis yet are at highest risk of severe disease – – a 75% hospitalization rate and a 1% case fatality rate. A case-control study in six U.S. states found that vaccinating women during the third trimester of pregnancy with Tdap vaccine provided 81% protection against pertussis to infants <2 months and 91% protection against hospitalized cases of pertussis.
Full Citation:
Skoff TH, Blain AE, Watt J et al.. 2017. The impact of the U.S. maternal Tdap vaccination program on preventing pertussis in infants <2 months of age: a case-control evaluation. Clinical Infectious Diseases. 65(12).
Title of Article: The impact of the U.S. maternal Tdap vaccination program on preventing pertussis in infants <2 months of age: a case-control evaluation
Author(s): Skoff TH, Blain AE, Watt J et al.
Publication Year: 2017
Publication Name: Clinical Infectious Diseases
Publication Volume: 65(12)
Publication Source URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754921/pdf/nihms927379.pdf
DOI (Digital Object Identifier): 10.1093/cid/cix724