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Knowledge Hub

Administering hepatitis B immune globulin to newborns in addition to vaccination prevents more infections and is cost-effective

In a study of different strategies for preventing hepatitis B infections in newborns in a Burmese refugee population with a high infection rate, administering hepatitis B immune globulin to newborns whose mothers test positive through a rapid diagnostic test — in addition to vaccinating all newborns with a birth dose — prevented twice as many infections in newborns than vaccination alone and was cost-effective (while the current strategy of providing immune globulin only after a confirmatory lab test was done was not). Thus, this strategy could be considered for similar marginalized or poor populations.

Full Citation:
Devine A, Harvey R, Min AM et al.. 2017. Strategies for the prevention of perinatal hepatitis B transmission in a marginalized population on the Thailand-Myanmar border: a cost-effectiveness analysis. BMC Infectious Diseases. 17(1).

Title of Article: Strategies for the prevention of perinatal hepatitis B transmission in a marginalized population on the Thailand-Myanmar border: a cost-effectiveness analysis

Author(s): Devine A, Harvey R, Min AM et al.

Publication Year: 2017

Publication Name: BMC Infectious Diseases

Publication Volume: 17(1)

Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/28793866/

DOI (Digital Object Identifier): 10.1186/s12879-017-2660-x

Topics: Economics & Return on Investment

Disease Vaccines: Hepatitis (A & B)

Immunization Terms: Cost-effectiveness

Countries: Myanmar | Thailand

WHO Regions: South-East Asia