VoICE Immunization Evidence
Global impact of rotavirus vaccination on childhood hospitalizations and mortality from diarrhea.
Immunization can decrease hospital admissions, thus alleviating pressure on overburdened health systems.
A literature review of impact evaluations from multiple countries following introduction of rotavirus vaccine showed a 32% median reduction in hospitalizations due to acute gastroenteritis (AGE) in children <1 year of age and a 38% median reduction in children <5 years. Laboratory confirmed rotavirus hospitalizations fell by 80% and 67% in children <1 and <5 years, respectively, after introduction of rotavirus vaccine. In high mortality setting, AGE decreased by 46% in children <5 years.
Burnett, E., Jonesteller, C. L., Tate, J. E., et al. 2017. Global impact of rotavirus vaccination on childhood hospitalizations and mortality from diarrhea.. The Journal of Infectious Diseases. 215(11), 1666-1672..