Publication

Indirect effect of 7-valent and 13-valent pneumococcal conjugate vaccines on pneumococcal pneumonia hospitalizations in elderly

Authored by:

Kislaya I, Rodrigues AP, Sousa-Uva M et al.

Full Citation:

Kislaya I, Rodrigues AP, Sousa-Uva M et al. 2019. Indirect effect of 7-valent and 13-valent pneumococcal conjugate vaccines on pneumococcal pneumonia hospitalizations in elderly. PLoS One. 14(1).

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Additional key concepts from this publication:

Immunization can help protect unimmunized children, adults and the elderly through herd effects.

Key Evidence: Hospitalization rates for pneumococcal pneumonia in adults 65 and older in Portugal — which had been increasing on average by 16% per year before pneumococcal conjugate vaccines became available — began to reverse once PCVs became available for infants. The reduction in the elderly, over expected rates, was greatest after the introduction of PCV13.