A community-based study in Vietnam found a high percent of children under five years of age were carrying pneumococcal bacteria in their noses and throats that were non-susceptible to commonly-used antibiotics. Of the strains tested, 18% were not susceptible to penicillin, 26% weren’t susceptible to cefotaxime, 76% were not susceptible to meropenem and 14% were not susceptible to all three nor to any of the “macrolide” drugs (e.g., erthromycin and azithromycin). However, 90% of the multi-drug resistant strains are serotypes that are in the 13-strain pneumococcal conjugate vaccine (PCV-13) and thus the introduction of a vaccine is expected to increase the susceptibility of circulating strains of the bacteria.
Full Citation:
Nguyen HAT, Fujii H, Vu HTT et al.. 2019. An alarmingly high nasal carriage rate of Streptococcus pneumoniae serotype 19F non-susceptible to multiple beta-lactam antimicrobials among Vietnamese children. BMC Infectious Diseases. 19(1).
Title of Article: An alarmingly high nasal carriage rate of Streptococcus pneumoniae serotype 19F non-susceptible to multiple beta-lactam antimicrobials among Vietnamese children
Author(s): Nguyen HAT, Fujii H, Vu HTT et al.
Publication Year: 2019
Publication Name: BMC Infectious Diseases
Publication Volume: 19(1)
Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/30866853/
DOI (Digital Object Identifier): 10.1186/s12879-019-3861-2
Topics: Antibiotic Resistance | Global Issues
Disease Vaccines: Pneumococcal disease/PCV/PPSV
Countries: Viet Nam
WHO Regions: Western Pacific