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Knowledge Hub

Large study in California finds significant reduction in need for antibiotics in vaccinated children

In a study evaluating the impact of PCV7 on 40,000 recipients and control subjects in northern California revealed that the vaccine could significantly decrease the need for antibiotics to treat the disease. The children who had received the vaccine displayed a 5.4% reduction in the number of antibiotic prescriptions and a 12.6% reduction in the use of “second-line antibiotics” compared to the controls. Additionally, when looking at children in the time period between their first dose and attainment of the age of 3.5 years, receiving the vaccine had prevented 35 antibiotic prescriptions per 100 fully vaccinated children.

Full Citation:
Fireman, B., Black, S.B., Shinefield, H.R., et al.. 2003. Impact of pneumococcal conjugate vaccine on otitis media. Pediatric Infectious Disease Journal. 22(1).

Title of Article: Impact of pneumococcal conjugate vaccine on otitis media

Author(s): Fireman, B., Black, S.B., Shinefield, H.R., et al.

Publication Year: 2003

Publication Name: Pediatric Infectious Disease Journal

Publication Volume: 22(1)

Publication Source URL: https://www.ncbi.nlm.nih.gov/pubmed/12544402

DOI (Digital Object Identifier): 10.1097/00006454-200301000-00006

Topics: Antibiotic Resistance | Global Issues

Disease Vaccines: Pneumococcal disease/PCV/PPSV

Countries: United States

WHO Regions: Americas