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Switching to PCV13 for infants reduced drug-resistant IPD by 78-96% in children under five

A large U.S. study of surveillance data examining the impact of switching from PCV7 to PCV13 for infants demonstrated how important vaccination is in combating antimicrobial resistance. While the incidence of antibiotic-resistant invasive pneumococcal disease (IPD) was increasing before the introduction of PCV13, drug resistant IPD declined 78-96% in children under five after the vaccine introduction.

Full Citation:
Moore MR, Link-Gelles R, Schaffner W et al.. 2015. Effect of use of 13-valent PCV in children on invasive pneumococcal disease in children and adults in the USA: analysis of multisite, population-based surveillance. Lancet Infectious Diseases. 15(3).

Title of Article: Effect of use of 13-valent PCV in children on invasive pneumococcal disease in children and adults in the USA: analysis of multisite, population-based surveillance

Author(s): Moore MR, Link-Gelles R, Schaffner W et al.

Publication Year: 2015

Publication Name: Lancet Infectious Diseases

Publication Volume: 15(3)

Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/25656600/

DOI (Digital Object Identifier): 10.1016/S1473-3099(14)71081-3