This study from South Africa demonstrates significant declines in invasive pneumococcal disease cases caused by bacteria that are resistant to one or more antibiotics. In fact, the rate of infections resistant to two different antibiotics declined nearly twice as much as infections that could be treated with antibiotics.
Full Citation:
Von Gottberg, A., de Gouveia, L., Tempia, S., et al.. 2014. Effects of pneumococcal vaccine in invasive pneumococcal disease in South Africa. New England Journal of Medicine. 371(20).
Title of Article: Effects of pneumococcal vaccine in invasive pneumococcal disease in South Africa
Author(s): Von Gottberg, A., de Gouveia, L., Tempia, S., et al.
Publication Year: 2014
Publication Name: New England Journal of Medicine
Publication Volume: 371(20)
Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/25386897/
DOI (Digital Object Identifier): 10.1056/NEJMoa1401914
Topics: Antibiotic Resistance | Global Issues
Disease Vaccines: Pneumococcal disease/PCV/PPSV | Pneumonia
Countries: South Africa
WHO Regions: Africa