What is the Knowledge Hub?
Explore the VoICE Knowledge Hub—a searchable database featuring the latest peer-reviewed research on immunization benefits, especially in low- and middle-income countries. Browse the Knowledge Hub using a variety of different filters to find vaccine evidence based on country, region, topic, or disease. Click on a tag to find more evidence on a specific area, such as the return on investment of vaccines or impacts of infectious disease outbreaks.
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Vaccinating both boys and girls against HPV can eradicate cancer-causing types of the virus
A Swedish-Finnish study conducted between 2007-2014 found that vaccinating both girls and boys against HPV (a gender-neutral vaccination strategy) could lead to the eradication of the most common cancer-causing types of the virus through stronger herd immunity. The study randomized HPV vaccination interventions across 33 towns (gender neutral HPV, girls-only HPV, and a control non-HPV vaccination), including 80,000 adolescents between ages 12 and 15. Results of general HPV screening at the age of 19 showed that gender-neutral vaccination prevented HPV infections much more effectively than vaccinating girls only.
Vänskä S, Luostarinen T, Baussano I et al.. 2020. Vaccination with moderate coverage eradicates oncogenic human papillomaviruses if a gender-neutral strategy is applied. The Journal of Infectious Diseases. 222(6).
Immunization can prevent long-term effects of meningococcal disease, such as hearing loss and psychological problems
A systematic literature review of studies of the long-term effects of invasive meningococcal disease in high-income countries found that children who survived the disease had a greater incidence of hearing loss and psychological problems, including attention-deficit/hyperactivity disorder (ADHD) than control groups or the general population. In addition, they had increased odds of death – one study showed more than a 25% greater mortality rate in this population than did the general public up to 30 years after having the disease.
Strifler L, Morris SK, Dang V et al.. 2016. The health burden of invasive meningococcal disease: a systematic review. Journal of the Pediatric Infectious Diseases Society. 5(4).