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Children with sickle cell disease stand to benefit enormously from PCV and Hib immunization

Nearly a quarter of a million children are born with sickle cell disease in Africa each year. Sickle cell disease was found to increase the risk of Hib infections by 13-fold and pneumococcal infections by 36 fold. This means that children with sickle cell disease stand to benefit enormously from PCV and Hib immunization.

Full Citation:
Ramakrishnan, M., Moisi, J.C., Klugman, K., et al.. 2010. Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis. The Lancet Infectious Diseases. 10(5).

Title of Article: Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis

Author(s): Ramakrishnan, M., Moisi, J.C., Klugman, K., et al.

Publication Year: 2010

Publication Name: The Lancet Infectious Diseases

Publication Volume: 10(5)

Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/20417415/

DOI (Digital Object Identifier): 10.1016/S1473-3099(10)70055-4

Topics: Health

Disease Vaccines: Haemophilus lnfluenzae type b (Hib) | Pneumococcal disease/PCV/PPSV

Immunization Terms: Review article

Countries: Global

WHO Regions: Africa