Nearly a quarter of a million children are born with sickle cell disease in Africa each year. Sickle cell disease was found to increase the risk of Hib infections by 13-fold and pneumococcal infections by 36 fold. This means that children with sickle cell disease stand to benefit enormously from PCV and Hib immunization.
Full Citation:
Ramakrishnan, M., Moisi, J.C., Klugman, K., et al.. 2010. Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis. The Lancet Infectious Diseases. 10(5).
Title of Article: Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis
Author(s): Ramakrishnan, M., Moisi, J.C., Klugman, K., et al.
Publication Year: 2010
Publication Name: The Lancet Infectious Diseases
Publication Volume: 10(5)
Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/20417415/
DOI (Digital Object Identifier): 10.1016/S1473-3099(10)70055-4
Topics: Health
Disease Vaccines: Haemophilus lnfluenzae type b (Hib) | Pneumococcal disease/PCV/PPSV
Immunization Terms: Review article
Countries: Global
WHO Regions: Africa