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HIV-exposed infants are more vulnerable to measles due to lower levels of antibodies

A small hospital-based study in India found that 6 month old infants born to HIV-infected women were 11 times more likely to lack measles antibodies than 6 month olds not exposed to HIV whether or not the exposed infants were themselves infected with HIV. The lack of antibodies in most HIV-exposed infants — making them more vulnerable to measles — may be due to lower levels of measles antibodies in HIV-infected mothers or to poorer transfer of antibodies to the fetus across the placenta.

Full Citation:
Jain S, Seth A, Khare S et al.. 2017. Seroprevalence of transplacentally acquired measles antibodies in HIV-exposed versus HIV-unexposed infants at six months of age. Indian Journal of Medical Research. 145(4).

Title of Article: Seroprevalence of transplacentally acquired measles antibodies in HIV-exposed versus HIV-unexposed infants at six months of age

Author(s): Jain S, Seth A, Khare S et al.

Publication Year: 2017

Publication Name: Indian Journal of Medical Research

Publication Volume: 145(4)

Publication Source URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663169/?report=printable

DOI (Digital Object Identifier):

Topics: Health

Disease Vaccines: Measles

Immunization Terms: HIV

Countries: India

WHO Regions: South-East Asia