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Knowledge Hub

Immunization with PCV10 in Mozambique reduced pneumococcal carriage rates in both HIV-infected and uninfected children

Within two years of the introduction of PCV10 in Mozambique, the percent of vaccinated children under five years of age with nasopharyngeal carriage of vaccine strains, declined equally in HIV-infected as in HIV-uninfected children. The vaccine-type carriage rates among both HIV-infected and uninfected vaccinated children after the vaccine was introduced were similar.

Pneumococcal nasopharyngeal carriage can be a precursor of invasive pneumococcal disease.

Full Citation:
Sigauque B, Moiane B, Massora S et al.. 2018. Early declines in vaccine type pneumococcal carriage in children less than 5 years old after introduction of 10-valent pneumococcal conjugate vaccine in Mozambique. Pediatric Infectious Disease Journal. 37(10).

Title of Article: Early declines in vaccine type pneumococcal carriage in children less than 5 years old after introduction of 10-valent pneumococcal conjugate vaccine in Mozambique

Author(s): Sigauque B, Moiane B, Massora S et al.

Publication Year: 2018

Publication Name: Pediatric Infectious Disease Journal

Publication Volume: 37(10)

Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/30216295/

DOI (Digital Object Identifier): 10.1097/INF.0000000000002134

Topics: Health

Disease Vaccines: Pneumococcal disease/PCV/PPSV

Immunization Terms: HIV

Countries: Mozambique

WHO Regions: Africa