Within two years of the introduction of PCV10 in Mozambique, the percent of vaccinated children under five years of age with nasopharyngeal carriage of vaccine strains, declined equally in HIV-infected as in HIV-uninfected children. The vaccine-type carriage rates among both HIV-infected and uninfected vaccinated children after the vaccine was introduced were similar.
Pneumococcal nasopharyngeal carriage can be a precursor of invasive pneumococcal disease.
Full Citation:
Sigauque B, Moiane B, Massora S et al.. 2018. Early declines in vaccine type pneumococcal carriage in children less than 5 years old after introduction of 10-valent pneumococcal conjugate vaccine in Mozambique. Pediatric Infectious Disease Journal. 37(10).
Title of Article: Early declines in vaccine type pneumococcal carriage in children less than 5 years old after introduction of 10-valent pneumococcal conjugate vaccine in Mozambique
Author(s): Sigauque B, Moiane B, Massora S et al.
Publication Year: 2018
Publication Name: Pediatric Infectious Disease Journal
Publication Volume: 37(10)
Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/30216295/
DOI (Digital Object Identifier): 10.1097/INF.0000000000002134
Topics: Health
Disease Vaccines: Pneumococcal disease/PCV/PPSV
Immunization Terms: HIV
Countries: Mozambique
WHO Regions: Africa