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Immunizing infants against typhoid can sharply reduce antibiotic-resistant cases

A study of the impact of typhoid conjugate vaccines in a hypothetical endemic population predicts that the number of antibiotic-resistant typhoid cases will decrease sharply if at least 80% of infants are vaccinated. However, the percent of cases that are resistant is not expected to change with vaccination, thus the disease will have to be nearly eliminated to get rid of all antibiotic resistant typhoid.

Full Citation:
Kaufhold S, Yaesoubi R, Pitzer VE. 2019. Predicting the impact of typhoid conjugate vaccines on antimicrobial resistance. Clinical Infectious Diseases. 68(2).

Title of Article: Predicting the impact of typhoid conjugate vaccines on antimicrobial resistance

Author(s): Kaufhold S, Yaesoubi R, Pitzer VE

Publication Year: 2019

Publication Name: Clinical Infectious Diseases

Publication Volume: 68(2)

Publication Source URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405272/pdf/ciy1108.pdf

DOI (Digital Object Identifier): 10.1093/cid/ciy1108

Topics: Antibiotic Resistance | Global Issues

Disease Vaccines: Typhoid

Countries: Global