A pooled analysis of three randomized controlled trials conducted in Nepal, Mali, and South Africa between 2011 and 2014 found that immunization during pregnancy provided protection against influenza to young infants from birth through 4 months of age. Protection against infant influenza was greatest in the first 2 months of life, with 56% efficacy, and the pooled efficacy of maternal vaccination to prevent infant laboratory-confirmed influenza up to 6 months of age was 35%.
Full Citation:
Omer SB, Clark DR, Madhi SA et al.. 2020. Efficacy, duration of protection, birth outcomes, and infant growth associated with influenza vaccination in pregnancy: a pooled analysis of three randomised controlled trials. The Lancet Respiratory Medicine. 8(6).
Title of Article: Efficacy, duration of protection, birth outcomes, and infant growth associated with influenza vaccination in pregnancy: a pooled analysis of three randomised controlled trials
Author(s): Omer SB, Clark DR, Madhi SA et al.
Publication Year: 2020
Publication Name: The Lancet Respiratory Medicine
Publication Volume: 8(6)
Publication Source URL: https://pubmed.ncbi.nlm.nih.gov/32526188/
DOI (Digital Object Identifier): 10.1016/S2213-2600(19)30479-5
Topics: Health
Disease Vaccines: Influenza
Countries: Mali | Nepal | South Africa
WHO Regions: Africa | South-East Asia