What is the Knowledge Hub?
Explore the VoICE Knowledge Hub—a searchable database featuring the latest peer-reviewed research on immunization benefits, especially in low- and middle-income countries. Browse the Knowledge Hub using a variety of different filters to find vaccine evidence based on country, region, topic, or disease. Click on a tag to find more evidence on a specific area, such as the return on investment of vaccines or impacts of infectious disease outbreaks.
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Rotavirus vaccination programs show significant short-term return on investments
In a UK cost-effectiveness analysis, which takes into account herd effect, the budget impact analysis demonstrated that the introduction of a rotavirus vaccine program could pay back between 58-96% of the cost outlay for the program within the first 4 years.
Atkins, K.E., Carroll, S., et al.. 2012. The cost-effectiveness of pentavalent rotavirus vaccination in England and Wales.. Vaccine. 30(48).
Measles infection suppresses the immune system for up to 3 years after infection
In a study of data from England & Wales, Denmark, and the US, it was shown that measles infection suppresses the immune system for up to 3 years after infection, increasing the risk of death due to other childhood infections during that time. This means that prevention of measles significantly impacts overall health during critical childhood years.
Mina, M.J., Metcalf, C.J. de Swart, R.L., et al. 2015. Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality. Science. 348(6235).