Evidence Briefs

Evidence Briefs consolidate the available scientific evidence on critical issues in immunization, providing concise insights for advocacy messaging.

Highlighting Global Issues and Immunization

The widespread benefits of immunization extend beyond individual health to address critical global challenges. Immunization plays an important role in protecting populations in the context of broader global issues such as climate change, conflict settings, and the rise of antibiotic-resistant microbes.

Gender Equity and Immunization

Gender equity and support for women and girls has a strong relationship with child health and access to immunization. Learn more about the latest research on the ways that immunization influences gender equity.

Immunization Economics: A Major Return on Investment

New economic analyses have shown that immunization supports more than health – vaccination can also have a significant return on investment and can help support national economies.

All Evidence Briefs

  • A Warming World Means Vaccination is More Important Than Ever

    A Warming World Means Vaccination is More Important Than Ever

    “The climate crisis threatens to undo the last fifty years of progress in development, global health, and poverty reduction, and […]

  • Breaking the Barriers: How Gender Equity Advances Immunization

    Breaking the Barriers: How Gender Equity Advances Immunization

    The COVID-19 pandemic has highlighted and exacerbated existing global gender inequities that impact the accessibility of immunizations to women and […]

  • Why Rotavirus Vaccine Introduction in Nigeria is a Milestone for Child Health

    Why Rotavirus Vaccine Introduction in Nigeria is a Milestone for Child Health

    In August 2022, Nigeria became the most recent country to introduce the rotavirus vaccine into its national immunization program. The […]

  • Leaving No Child Behind: Zero-Dose and UHC

    Leaving No Child Behind: Zero-Dose and UHC

    December 12th is recognized worldwide as Universal Health Coverage (UHC) day. Universal health coverage “ensures all people, everywhere, can get […]

  • HPV Vaccines: New Momentum in Eliminating Cervical Cancer

    HPV Vaccines: New Momentum in Eliminating Cervical Cancer

    In August of 2020, the World Health Assembly adopted the global strategy to accelerate the elimination of cervical cancer as a public health problem. Vaccines against the human papillomavirus (HPV) can prevent the vast majority of the world’s 570,000 annual cases of cervical cancer. Increasing access to the HPV vaccine, as well as screening and…

  • Maternal Immunization: Protected Together

    Maternal Immunization: Protected Together

    Maternal immunization is a promising strategy for protecting mothers, the developing fetus, and young infants during a particularly vulnerable time in their lives – especially in low- and middle-income countries where morbidity and mortality among women and their children is high. During pregnancy, vaccines allow antibodies from the mother to cross into the placenta, protecting…

  • The Power of a Single Dose: Evidence for a Single-Dose HPV Vaccine Schedule 

    The Power of a Single Dose: Evidence for a Single-Dose HPV Vaccine Schedule 

    HPV Vaccination: A Critical Cancer Prevention Tool  Since 2006, vaccines have been available to protect against human papillomavirus (HPV), an […]

  • The Other Pandemic: The Promise of TB Vaccines

    The Other Pandemic: The Promise of TB Vaccines

    What disease has infected millions of people, killing an estimated 1.5 million people a year, without drawing a fraction of the attention of the COVID-19 pandemic? The answer is tuberculosis (TB). New, more effective vaccines are needed to reduce the morbidity and mortality of TB, fight the rising threat of AMR, and address inequities in…

  • Vaccines are Key in Combating Antimicrobial Resistance (AMR)

    Vaccines are Key in Combating Antimicrobial Resistance (AMR)

    Antimicrobial resistance (AMR) is a growing threat to the health of children worldwide. New evidence shows how vaccines are one promising way to combat the global spread of AMR. New research on typhoid conjugate vaccines (TCV) shows how immunization can protect children, families, and communities against the emergence of dangerously resistant superbugs.

  • Integration: Leveraging Immunization for Health System Strengthening

    Integration: Leveraging Immunization for Health System Strengthening

    The battle to eliminate polio is one example of how immunization integration can be leveraged to strengthen health systems and build vaccine acceptance. Integration is one of the three pillars of the Endgame Strategy and is highlighted as a strategic priority in the Immunization Agenda 2030 (IA2030) and in Gavi’s 5.0 strategy.

  • World Immunization Week 2021 Social Media Toolkit

    World Immunization Week 2021 Social Media Toolkit

    With all eyes on vaccines, World Immunization Week 2021 (April 24-30) offers an unprecedented opportunity to build public trust in the value of all vaccines and help build long-term support for immunization. Our VoICE social media toolkit provides messaging for immunization advocates on the vital role that vaccines play in strengthening economies, equity, and health…

  • The Value of Vaccines: Investments in Immunization Yield High Returns

    The Value of Vaccines: Investments in Immunization Yield High Returns

    Vaccines provide incredible value in more ways than one. In addition to saving the lives of millions of children, vaccine programs also provide a high economic return on investment. New research demonstrates the incredible impact and value of vaccination for policymakers.

  • Equity and Immunization: Shrinking the Gaps

    Equity and Immunization: Shrinking the Gaps

    Although more children than at any point in history are now protected against vaccine-preventable diseases, millions of zero-dose children are still missing out on the life-saving benefits of immunization entirely. These children often live in the world’s most marginalized communities where inequities are clustered and compounded by poverty, geography, gender, and conflict. In order to…